*sox18* in the bag

From: Damien Broderick (d.broderick@english.unimelb.edu.au)
Date: Tue Mar 28 2000 - 07:10:47 MST


I hear tonight on the Oz news that the *sox18* gene, which writes the Sox18
protein, has been decoded by Brisbane researchers. I can't find anything
yet on the net, but I'm guessing this happened at the Australian Research
Council CENTRE FOR MOLECULAR AND CELLULAR BIOLOGY in Queensland (sorry,
their caps).
`Sox18,' they said two years ago, `is an endothelian-specific gene which is
probably involved in transcriptional control of endothelium-specific
genes.' Tonight's news report sez it's the (or a) key gene controlling
angiogenesis. Switch it on locally, and you'd get fast growth of blood
supply where you need it. Switch it off with statins or other antagonists,
and you stop tumor vascularisation cold. Or so I surmise.

Damien



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