From: CurtAdams@aol.com
Date: Mon Jul 29 2002 - 19:00:46 MDT
In a message dated 7/29/02 15:19:31, rms2g@virginia.edu writes:
>Well, heteroplasmy and genetic drift within mitochondrial populations
>have been shown to occur in aging and are sufficient to explain many of
>its features.
It's certainly possible that changes to mtDNA during life are a major factor
in aging. It's just that any genes that regulate such processes must be in
the nucleus, since there's just no room in the mtDNA.
>differences in the mtDNA
>of the oocytes (my next project) could cause variation between siblings with
>the same mother
Well, good luck, but mtDNA transmission has been studied in some detail and
chimerism is relatively rare. It would have to be nearly universal to knock
out the genetic signal, and it's certainly not that.
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