From: Doug Skrecky (oberon@vcn.bc.ca)
Date: Wed Jan 27 1999 - 02:30:06 MST
Authors
Paleologos M. Cumming RG. Lazarus R.
Institution
Department of Public Health and Community Medicine, Faculty of Medicine,
University of Sydney, New South Wales, Australia.
Title
Cohort study of vitamin C
intake and cognitive impairment.
Source
American Journal of Epidemiology. 148(1):45-50, 1998 Jul 1.
Abstract
To test the hypothesis that vitamin C protects against
cognitive impairment, the authors conducted a cohort
study (n=117) in a retirement community in Sydney,
Australia. Vitamin C intake was assessed at baseline (1991)
with a semiquantitative food frequency questionnaire, and cognitive function
was assessed 4 years later (1995). After adjustment for age, sex, smoking,
education, total energy intake, and use of psychotropic medications,
consumption of vitamin C supplements was associated with a
lower prevalence of more severe cognitive impairment (based on scores on the
Mini-Mental State Examination; adjusted odds ratio=0.39, 95% confidence
interval 0.18-0.84). There were no associations between
vitamin C intake and scores on tests of verbal and category
fluency. This study suggests that vitamin C
might protect against cognitive impairment.
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