From: Robert J. Bradbury (bradbury@aeiveos.com)
Date: Tue Nov 19 2002 - 21:22:55 MST
Poor Jeff,
He isn't following his own quotes...
> "When I am working on a problem I never think about
> beauty. I only think about how to solve the problem.
> But when I have finished, if the solution is not
> beautiful, I know it is wrong."
> - Buckminster Fuller
This press release is clearly "not beautiful"...
> http://www.eurekalert.org/pub_releases/2002-11/su-rcd111902.php
"Kool explained. "It's still not completely clear how that works,
but it is clear that once telomeres reach the critically short length
of 3,000 to 5,000 base pairs, they enter senescence and die."
Oppps, mistake number one -- as Judith Campisi explained at Extro 4
senescent cells *do not* die.
"The link between organism aging and cell aging is less clear, but there
very likely is a link," he noted. "On the other hand, it is pretty
clear that telomere length governs how long an individual cell lives."
Not! A cell with short telomeres can live a very long time as
a "scenescent" cell. Most likely the determinant of cellular
longevity relates to the accumulation of mutations in essential
genes.
Robert
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