From: Extropian Agro Forestry Ventures Inc. (megao@sk.sympatico.ca)
Date: Mon Jun 10 2002 - 19:33:30 MDT
I will post some info and fwd a couple of things separately
immune modulators especially ones with low overall toxicity are good
choices for long term support.
Non-hallucingenic cannabinoids are classed as neuroprotective
antioxidants. Cannabidiol is a good candidate. Find a hemp farmer and
go get a few pounds of buds. Freeze or gently dry and incorporate into
foods.
Phase2 enzyme inducers of various origins most notably crucifer sprouts
or extracts therefrom have functionality in reducing neurological trauma
from disease processes.
Omega3 oils including GLA are long standing supportative chemistry for
nerve cells.
Alpha lipoic acid especially in quite large doses has in the literature
shown efficacy as supportative on a systemic basis.
Piracetam and its related pyrrolidinone derivatives has fundamental
utility to optimize oxygen efficiency in mitichondria. Nerve cells
under stress need this kind of support. Go heavy on this 1-5 grams/
day would not be excessive.
Recently 2 neurologists from Stanford presented a paper at FASEB about
the immune aspects of the statin drugs (ex-lipitor)commonly used to
block cholesterol. There is a strong recommendation to apply them to
MS. They are dose dependant so don't skimp. 80mg is safe for long term
use. Split this dose AM/PM
antioxidants from the broad classification of the flavonoids,
anthocyanins, ponlphenols and their complex relatives the condensed and
hydrolyzable tannins are a strong personal recommendation for dietary
support. Include the soy isoflavones in this category.
The interferons, if your drug plan will cover them are good at
forestalling damaging plaque development.
My wife has MS so I have a long term R&D interest in this area.
We are personally involved in making a business of food products made to
order with many of the aforementioned items so I have an ongoing
professional interest in this as well.
There is an antiviral drug as well that for some has prevented fatique
related to MS.
"Smigrodzki, Rafal" wrote:
>
>
> The newest results I heard about is the use of induction therapy with
> mitoxanthrone and steroids at time of diagnosis. This reportedly
> resulted in a 90% reduction in the frequency of relapses. Most likely
> the neurologist threating your friend will initally use interferons or
> Copaxone, leaving mitoxanthreone for the cases progressing despite
> therapy. Stem cell transplants are also presently used only in
> advanced cases, as an investigational therapy but with some
> spectacular results - arrest in the rate of progression in the vast
> majority of patients.
>
> Probably the most practically feasible course of action for a patient
> who was only recently diagnosed is to try to convince the treating
> physician to start her/him on Rebif, and to try to enroll in any
> experimental studies, especially reagrding the use of combination
> interferon/Copaxone therapy.
>
> Rafal Smigrodzki
> MD-PhD, Dept Neurology UPMC Pittsburgh
This archive was generated by hypermail 2.1.5 : Sat Nov 02 2002 - 09:14:43 MST