From: Damien Broderick (d.broderick@english.unimelb.edu.au)
Date: Tue Apr 11 2000 - 22:44:30 MDT
>Today CNN carried a story about an aging gene called p-21 that is responsible
>for expressing aging related disease genes
p21 is, the web tells me (with various further hotlinks) at
http://www.genlink.wustl.edu/teldb/pteldb/pfile/p21.html
< a cyclin-dependent kinase inhibitor 1. Induced by p53, and may mediate
its role in response to DNA damage. >
p53 is one of the most famous genes linked to cancer, since it inhibits
transformation into the malignant state except when damaged. So p21 must be
part of a control feedback loop. Robert?
Damien
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