Organoids

Organoid cryopreservation

• Cryopreservation of human cortical organoids using vitrification
• Functional recovery of the adult murine hippocampus after cryopreservation by vitrification

Retinal organoids

• Optogenetic activation of vascularized human retinal organoids (2024)
• Retinal organoids from pluripotent stem cells efficiently recapitulate retinogenesis

See biosight for more information.

Olfactory organoids

TODO: combine both taste (GPCR + ion channel receptors) and also olfaction into a single organoid; is there good reason to not do this?

Consider the olfactory perception enhancements from ?genetic-modifications.

auditory organoids

engineered hair cells

bat, dolphin, mouse, human.

Other

Harnessing synthetic biology to engineer organoids and tissues this has a good overview of prospective techniques for programmable developmental biology, cell-cell adhesion, multi-state genetic circuits to control morphology, optogenetic chimeric receptors, synNotch receptor system, synthetic diffusive morphogen system using a synthetic receptor "such as MESA", synthetic cell-cell adhesion molecules, multi-fate synthetic circuits, juxtacrine signaling, diffusible morphogens, differential cell adhesion, etc.

Patterning of brain organoids derived from human pluripotent stem cells

Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output (2018)

See also morphogenesis for patterned control of organoid development.

see also bioprinting