Rotavirus RNA replication requires a single-stranded 3'end for efficient minus-strand synthesis De novo initiation of viral RNA-dependent RNA synthesis Terminal nucleotidyl transferase activity of recombinant Flaviviridae RNA-dependent RNA polymerases: implication for viral RNA synthesis Initiation of viral RNA-dependent RNA polymerization A comparison of viral RNA-dependent RNA polymerases Different de novo initiation strategies are used by influenza virus RNA polymerase on its cRNA and viral RNA promoters during viral RNA replication Conformational changes involved in initiation of minus-strand synthesis of a virus-associated RNA A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase Reinitiated viral RNA-dependent RNA polymerase resumes replication at a reduced rate Control of template positioning during de novo initiation of RNA synthesis by the bovine viral diarrhea virus NS5B polymerase Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase Template Requirements for RNA Synthesis by a Recombinant Hepatitis C Virus RNA-Dependent RNA Polymeras Towards an atomic resolution understanding of the influenza virus replication machinery Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution