from https://patentscope.wipo.int/search/docservicepdf_pct/id00000037440163/PAMPH/WO2017062311.pdf Metchnikoff’s Hypothesis of Aging (Metchnikoff E., 1901) Rate of Living Theory of Aging (Rubner M., 1908; Pearl R., 1928) The Calorie Restriction Theory of Aging (McCay C., 1935) The Free Radical Theory of Aging (Harmon D., 1956) The Somatic Mutation Theory of Aging (Szilard L., 1959) The Methylation Theory of Aging (Vanyushin B., 1967) Disposable Soma Theory of Aging (Kirkwood T. and Rose M., 1991) Inflammaging Theory of Aging (Franceschi C., 2007) Retrotransposon Theory of Aging (Laurent G., 2010) Redox Stress Hypothesis of Aging (Sohal R., 2012)