TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model.
Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation.
PGC-1{alpha} serine570 phosphorylation and GCN5-mediated acetylation by Angiotensin II drive catalase downregulation and vascular hypertrophy.
Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance.
Pyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins.
Anthocyanin-rich red grape extract impedes adenoma development in the ApcMin mouse: Pharmacodynamic changes and anthocyanin levels in the murine biophase
Dietary Cyanidin 3-O-ß-D-Glucoside-Rich Purple Corn Color Prevents Obesity and Ameliorates Hyperglycemia in Mice 
Dietary Blueberry Attenuates Whole-Body Insulin Resistance in High Fat-Fed Mice by Reducing Adipocyte Death and Its Inflammatory Sequelae1–3,
Antitumor effect of anthocyanin fractions extracted from red soybeans and red beans in vitro and in vivo.
Antitumor effect of hydrolyzed anthocyanin from grape rinds and red rice
Purple Sweet Potato Color Alleviates D-galactose-induced Brain Aging in Old Mice by Promoting Survival of Neurons via PI3K Pathway and Inhibiting Cytochrome C-mediated Apoptosis.
Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway.
Inhibition of epidermal growth factor receptor signaling pathway by delphinidin, an anthocyanidin in pigmented fruits and vegetables.
Delphinidin inhibits cell proliferation and invasion via modulation of Met receptor phosphorylation.
Targeting phosphoinositide 3-kinase gamma to fight inflammation and more.
PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?
Small molecule inhibitors of phosphoinositide 3-kinase (PI3K) delta and gamma.
Signaling through PI3Kgamma: a common platform for leukocyte, platelet and cardiovascular stress sensing.

Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells
The SETD8/PR-Set7 Methyltransferase Functions as a Barrier to Prevent Senescence-Associated Metabolic Remodeling
Integrin beta 3 regulates cellular senescence by activating the TGFβ pathway
Restoration of the thymus in aging mice by in vivo zinc supplementation
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Machine learning for predicting lifespan-extending chemical compounds