Authors
Sheela CG. Kumud K. Augusti KT.
Title
Anti-diabetic effects of onion and garlic
sulfoxide amino acids in rats [letter].
Source
Planta Medica. 61(4):356-7, 1995 Aug.
Abstract
On oral administration of onion (Allium cepa L.) and garlic (A. sativum L.)
sulfoxide amino acids viz., S-methylcysteine sulfoxide (SMCS) and
S-allylcysteine sulfoxide (SACS) to alloxan-diabetic rats for a month, their
diabetic condition, being characterized by glucose intolerance, weight loss,
depletion of liver glycogen, etc., was ameliorated as comparable to rats
treated with glibenclamide and insulin. However, only the last two drugs
significantly increased the conversion of labelled acetate to liver
cholesterol which indicates a deterrent effect of the allium products against
the synthesis of a risk factor.