Authors
Jacobsen BK. Knutsen SF. Fraser GE.
Institution
Institute of Community Medicine, University of Tromso, Norway.
Title
Does high soy milk
intake reduce prostate cancer incidence? The Adventist
Health Study (United States) [see comments].
Comments
Comment in: Cancer Causes Control 1998 Dec;9(6):541-3
Source
Cancer Causes & Control. 9(6):553-7, 1998 Dec.
Abstract
OBJECTIVES: Recent experimental studies have suggested that isoflavones (such
as genistein and daidzein) found in some soy products may
reduce the risk of cancer. The purpose of this study was to evaluate the
relationship between soy milk, a beverage
containing isoflavones, and prostate cancer incidence. METHODS: A prospective
study with 225 incident cases of prostate cancer in 12,395 California
Seventh-Day Adventist men who in 1976 stated how often they drank
soy milk. RESULTS: Frequent consumption
(more than once a day) of soy milk was
associated with 70 per cent reduction of the risk of prostate cancer
(relative risk = 0.3, 95 percent confidence interval 0.1-1.0, p-value for
linear trend = 0.03). The association was upheld when extensive adjustments
were performed. CONCLUSIONS: Our study suggests that men with high
consumption of soy milk are at reduced risk
of prostate cancer. Possible associations between soy bean
products, isoflavones and prostate cancer risk should be further
investigated.