RE:Einsteins brain

Gina Miller (nanogirl@halcyon.com)
Sun, 25 Apr 1999 23:22:32 -0700

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On the Brain of a Scientist: Albert Einstein" was published in 1985 in = the journal Experimental Neurology (vol. 88, pages 198-204, 1985) and = written by Marian C. Diamond, Arnold B. Scheibel, Greer M. Murphy and = ...Thomas Harvey!

Compared to the brains of the 11 normal men, the ratios of neurons to = glial cells in Einstein=92s brain were smaller in all 4 areas studied. = However, when the numbers were examined more closely with statistics, = only 1 area showed a difference - the ratio in the left area 39. So in = the left area 39, Einstein=92s brain had fewer neurons to glial cells = than the normal brains. In other words, there were more glial cells for = every neuron in Einstein=92s brain.
The authors concluded that the greater number of glial cells per neuron = might indicate the neurons in Einstein=92s brain had an increased = "metabolic need" - they needed and used more energy. In this way, = perhaps Einstein had better thinking abilities and conceptual skills.=20

A second paper describing Einstein's brain was published in 1996. = Einstein's brain weighed only 1,230 grams which is far less than the = average adult male brain (about 1,400 grams). The authors also reported = that the thickness of Einstein's cerebral cortex (area 9) was thinner = than that of five control brains. However, the DENSITY of neurons in = Einstein's brain was greater. In other words, Einstein was able to pack = more neurons in a given area of cortex.=20 The importance of these differences is still unknown. There are still = many questions about how the brain constructs personality, builds = intelligence and forms creativity. Perhaps future studies of the brains = of other geniuses will reveal what makes these people such giants.=20

Diamond MC, Scheibel AB, Murphy GM Jr, Harvey T Neuron:glial ratios were determined in specific regions of Albert = Einstein's cerebral cortex to compare with samples from 11 human male = cortices. Cell counts were made on either 6- or 20-micron sections from = areas 9 and 39 from each hemisphere. All sections were stained with the = Kluver-Barrera stain to differentiate neurons from glia, both astrocytes = and oligodendrocytes. Cell counts were made under oil immersion from the = crown of the gyrus to the white matter by following a red line drawn on = the coverslip. The average number of neurons and glial cells was = determined per microscopic field. The results of the analysis suggest = that in left area 39, the neuronal: glial ratio for the Einstein brain = is significantly smaller than the mean for the control population (t =3D = 2.62, df 9, p less than 0.05, two-tailed). Einstein's brain did not = differ significantly in the neuronal:glial ratio from the controls in = any of the other three areas studied.=20

Gina "Nanogirl" Miller
Nanotechnology Industries
Web:
http://www.nanoindustries.com
E-mail:
nanogirl@halcyon.com

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On the Brain of a Scientist: Albert Einstein" was published in = 1985 in=20 the journal Experimental Neurology (vol. 88, pages 198-204, 1985) = and=20 written by Marian C.=20 Diamond, Arnold B. Scheibel, Greer M. Murphy and ...Thomas Harvey!
 
Compared to the brains of the 11 normal men, the ratios of neurons = to glial=20 cells in Einstein’s brain were smaller in all 4 areas studied. = However,=20 when the numbers were examined more closely with statistics, only 1 area = showed=20 a difference - the ratio in the left area 39. So in the left area 39,=20 Einstein’s brain had fewer neurons to glial cells than the normal = brains.=20 In other words, there were more glial cells for every neuron in = Einstein’s=20 brain.
The authors concluded that the greater number of glial cells per = neuron=20 might indicate the neurons in Einstein’s brain had an increased=20 "metabolic need" - they needed and used more energy. In this = way,=20 perhaps Einstein had better thinking abilities and conceptual skills. =
 
A second paper describing Einstein's brain was published in 1996.=20 Einstein's brain weighed only 1,230 grams which is far less than the = average=20 adult male brain (about 1,400 grams). The authors also reported that the = thickness of Einstein's cerebral cortex (area 9) was thinner than that of five control brains. However, = the DENSITY=20 of neurons in Einstein's brain was greater. In other words, Einstein was = able to=20 pack more neurons in a given area of cortex.=20

The importance of these differences is still unknown. There are still = many=20 questions about how the brain constructs personality, builds = intelligence and=20 forms creativity. Perhaps future studies of the brains of other geniuses = will=20 reveal what makes these people such giants.

Diamond MC, Scheibel AB, Murphy GM Jr, Harvey T

Neuron:glial ratios were determined in specific regions of Albert = Einstein's=20 cerebral cortex to compare with samples from 11 human male cortices. = Cell counts=20 were made on either 6- or 20-micron sections from areas 9 and 39 from = each=20 hemisphere. All sections were stained with the Kluver-Barrera stain to=20 differentiate neurons from glia, both astrocytes and oligodendrocytes. = Cell=20 counts were made under oil immersion from the crown of the gyrus to the = white=20 matter by following a red line drawn on the coverslip. The average = number of=20 neurons and glial cells was determined per microscopic field. The = results of the=20 analysis suggest that in left area 39, the neuronal: glial ratio for the = Einstein brain is significantly smaller than the mean for the control = population=20 (t =3D 2.62, df 9, p less than 0.05, two-tailed). Einstein's brain did = not differ=20 significantly in the neuronal:glial ratio from the controls in any of = the other=20 three areas studied.

Gina "Nanogirl" Miller
Nanotechnology = Industries
Web:
http://www.nanoindustries.com<= BR>E-mail:
nanogirl@halcyon.com

 

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