Re: Health risks [was Re: Biotech rice (roundup)]

From: Robert J. Bradbury (bradbury@www.aeiveos.com)
Date: Tue Aug 24 1999 - 13:00:15 MDT


On Tue, 24 Aug 1999 CurtAdams@aol.com wrote:

>
> On Tue, 24 Aug 1999 Entropyfoe@aol.com wrote:
>
> > Monsanto's new genetically engineered soybean has been modified so
> > that it can survive heavy doses of Monsanto's poisonous weed-killing
> > herbicide, Roundup (glyphosate).

Actually, Entropyfoe didn't write it, I did, but I took it from
the web page the message mentions.

>
> The soybean isn't engineered to take particularly high doses,
>just the same kind of dose as corn already gets.

Just another case of slightly distorting the facts... :-)

>
> You are aware that both the incidence of and the mortality from cancer have
> been dropping for several years and that the age-adjusted risk of cancer is
> probably lower than it's ever been before, right?
>
Now I am. :-)
But I would have to believe that the major reasons for this are:
 a) A decline in smoking.
 b) More health awareness (for things like breast exams).
 c) Air & water pollution laws instituted in the '60s and '70s.
    [Improvements in these laws at this time are starting to
     produce very marginal benefits.]
 d) An increased understanding of radon causing cancer.

Most of the cancers are now related to people giving themselves
megadoses of carcinogens (in cigarrete smoke or alcohol).
There is a small but important fraction that result from high
levels of exposures in specific industries, such as agriculture.

The remaining risk factors are probably highly genetic and
it won't be until we have the complete genome, and the
polymorphisms in genes responsible for -- tumor promotion &
suppression, DNA repair, oxidative stress resistance,
antioxidant nutrient absorption, toxin metabolism, the
levels of various growth factors and the genes responsible
for determing what mutated peptide fragments are displayed to
your immune system (and probably a couple of more paths
I can't think of right now) -- are completely known and on
a chip that can run a test in your doctor's office will we fully
understand who is at risk and how aggressive we should be
with monitoring them. Maybe in 5-10 years.

Given this number of pathways are involved, I'm not surprised
that ~1/3 of people die from cancer. The rest probably have
the "super"-gene variants (alleles) in all of these pathways.

Robert



This archive was generated by hypermail 2.1.5 : Fri Nov 01 2002 - 15:04:52 MST