From: Doug Skrecky (oberon@vcn.bc.ca)
Date: Fri Oct 02 1998 - 15:46:53 MDT
From: sbharris@ix.netcom.com(Steven B. Harris)
Newsgroups: sci.med.nutrition,misc.health.alternative
There's another problem with interpreting rodent DHEA experimental
results, and that is the fact that DHEA causes proliferation of liver
peroxisomes in rodents, but apparently does not do so in humans. This
proliferation of these organelles which are full of nasty oxidative
enzymes is thought to underlie the hepato-carcinogenic effect of the
stuff in rodents. So it's not at all clear that humans are at the same
risk, even with the same megadose of DHEA.
Steve
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