Re: Immortal Human Cells & wonderful news

From: Anders Sandberg (asa@nada.kth.se)
Date: Thu Jan 15 1998 - 03:20:06 MST


Damien Broderick <damien@ariel.ucs.unimelb.edu.au> writes:

> >Could it be that telomerase is harmful in some tissues?
>
> My guess is that its production is inactivated in somatic cells as a
> general prophylaxis against cancer. Immortal tumors do, indeed, switch
> telomerase production back on. If we wish to extend our lives by tweaking
> this mechanism, we're going to have to be *very careful*...

Yes, there is likely a balance between cell regeneration and cancer risk.

Something I have been thinking of is if we could find ways of making
the control machinery of cell division more robust. I have the
impression that the p53 control is far too easily sabotaged by
mutations; a double check there would be nice.

-- 
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Anders Sandberg                                      Towards Ascension!
asa@nada.kth.se                            http://www.nada.kth.se/~asa/
GCS/M/S/O d++ -p+ c++++ !l u+ e++ m++ s+/+ n--- h+/* f+ g+ w++ t+ r+ !y


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