Re: life extension and the FDA (was: RE: EVOLUTION: Germline engineering)

From: Robert J. Bradbury (bradbury@aeiveos.com)
Date: Sat Nov 30 2002 - 09:01:10 MST


On Fri, 29 Nov 2002, Ramez Naam wrote:

> For example, you could get your drug approved as a treatment for
> cardiovascular disease if you showed that 70 year olds who took your
> drug for a year were 50% less likely to die of a heart attack over the
> next 5 years than 70 year olds who did not take your drug. (Indeed,
> 50% would be an absolutely huge effect.)
>
> Now, this hypothetical drug might be acting on fundamental ageing
> processes, not just heart disease.

The drug you have just described is very similar to Alteon's ALT-711.
It is going through clinical trials to lower blood pressure -- but it
basically prevents and/or reverses protein glycation.

Robert



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