From: Doug Skrecky (oberon@vcn.bc.ca)
Date: Sat Nov 09 2002 - 06:54:50 MST
This is the 72'nd update of my fly longevity experiments. Average
temperature was 24.7 C during this run. Here I retest bergamot,
CDP-choline, and citrulline at some higher doses.
The 1/4 tsp dose of bergamot leaf again increased survival. A
published experiment found that black tea also increased survival due to
the presence of a volatile iron chelator, which prevented iron
accumulation in fly tissues. I suspect that this volatile iron chelator,
which is not present in green tea, may have been derived from the bergamot
leaf, which is added to some black teas. Since I used bergamot leaf
powder, rather than brewing a tea, the leaf powder may have released this
voltaile iron chelator gradually. At any rate, this is one theory
explaining why bergamot appears to work at a low dose. The high dose
might be inducing a marginal iron deficiency.
CDP-choline once again found the 500 mg dosage edging out the 250 mg
dose, but mild toxicity appears to have set in at the 1000 mg dose. The
1/2 tsp dose of citrulline yielded a positive hit.
Run #72 Percent Survival on Day
supplement 7 16 25 34 45 54 63
____________________________________________
control 93 89 61 25 7 0 -
bergamot leaf 1/4 tsp 100 86 81 62 19 0 -
bergamot leaf 1 tsp 100 63 58 32 16 0 -
CDP-choline 250 mg 100 100 65 30 15 0 -
CDP-choline 500 mg 100 75 71 46 11 0 -
CDP-choline 1000 mg 89 79 68 25 4 0 -
citrulline 1/2 tsp 96 91 87 61 26 17 0
citrulline 1 tsp 100 84 68 32 4 0 -
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