From: Rafal Smigrodzki (rms2g@virginia.edu)
Date: Mon Jul 29 2002 - 16:20:12 MDT
I (Rafal (rms2g@virginia.edu) didn't ask the following questions:
> Why mice age a lot faster than humans? Have there been any
>mtDNA genes mapped in humans that protect our mtDNA?
Curt Adams wrote:
No. We know everything in mtDNA (which is virtually nothing) and there
are no DNA-involved genes whatsoever. Aging is also not particularly
affected by the mother, which nixes an mtDNA origin on genetic grounds.
### Well, heteroplasmy and genetic drift within mitochondrial populations
have been shown to occur in aging and are sufficient to explain many of its
features. You can have mitochondrial inheritance in the absence of maternal
pattern of inheritance - chimerism in the ovary and differences in the mtDNA
of the oocytes (my next project) could cause variation between siblings with
the same mother.
Rafal
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