From: Mike Linksvayer (ml@gondwanaland.com)
Date: Thu Apr 11 2002 - 20:46:13 MDT
On Wed, 2002-04-10 at 05:23, Robert J. Bradbury wrote:
> On 9 Apr 2002, Mike Linksvayer wrote:
> > CR doesn't appear to work by slowing down metabolism, though it is
> > systemic, details unknown as noted.
>
> I'd disagree. I'm moderately certain that its been shown in
> multiple studies, including primate studies, that CR lowers
> body temperature (and so therefore metabolism must be lower).
>
> I suppose one could split hairs here and propose that only
> disposal of excess mitochondrial hydrogen ion gradient
> (that contributes to heat production) is lower and not
> actual "metabolism", but thats a very fine distinction.
Thanks. I was hoping someone knowledgable would swat my bio-ignoramous
gleanings. Two ideas/questions: Could metabolism be more efficient
rather than lower? Could lower metabolism be an effect of CR, but not
a/the life extension mechanism? Human metabolism varies quite a bit
among individuals (and individuals "practicing CR", though there's no
rigorous definition that), but I haven't heard of any correlation with
longevity.
> [Mike, if you have the full post to the CR list with references,
> I'd appreciate a copy of it. Thanks.]
Original post:
http://groups.yahoo.com/group/crsociety/message/18786
References:
http://groups.yahoo.com/group/crsociety/message/18806
Mike Linksvayer
http://gondwanaland.com/ml/
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