From: Alejandro Dubrovsky (s328940@student.uq.edu.au)
Date: Thu Feb 07 2002 - 04:55:16 MST
On Thu, 2002-02-07 at 15:39, Damien Broderick wrote:
> At 08:24 PM 2/4/02 -0500, Dan Clemmensen wrote:
>
> >The forward directions of the two strands are in
> >opposite directions. One end of a strand is called 3' (three-prime) and
> >the other is 5', but I've forgotten which is which.
>
> but then threw in, for fun, this possibly misleading snippet:
>
> > RNA polymerase... runs down the "wrong"
> >(i.e. antisense) DNA strand toward its 5' end
>
> Just to make it clear: DNA is transcribed from the 5-prime to the 3-prime
> end. What happens when the uncoiling hits the centrome? Beats me.
No, i think Dan Clemmensen was correct. RNA Polymerase goes from the 3'
to the 5', so the RNA produced is created in the 5' to 3' direction and
can be processed by the ribosomes while transcription is still going on
(in prokaryotes that is, in eukaryotes this simultaneity doesn't occur,
but the direction of transcription is still the same).
Alejandro
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