Re: Cornering the causes of aging (was Re: AGING: Accumulation of DNA damage)

From: CurtAdams@aol.com
Date: Wed Jun 28 2000 - 09:33:34 MDT


In a message dated 6/27/00 9:32:57 AM, joao.magalhaes@fundp.ac.be writes:

>It is logical that if lifespan does not exceed 120
>then lethal mutations acting
>at late ages can accumulate in all organs; but these
>are pathologies, not basic causes of aging).

If you have *nothing* but a variety of accumulating late-acting
pathologies, that alone will create "aging": increasing mortality
plus decreasing function accumulating thoughout life, following
a roughly Gompertzian curve. So the pathologies can indeeed be
the basic cause of aging.



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