MHV and tumour cell lines

[tim at besancon.net]

Hi everybody,
We work on murine bone marrow transplantation using WEHI and A20 cells
in a GvL model. Since the introduction of these cells we have observed
atypical survival rates after BMT. We suspect viral contamination of the
tumour cell lines (most probably MHV, after the histopathological
analysis). Does anybody have some similar experience or advice on this
situation? Any reference on viral contamination of murine tumour cell
lines will be also welcome.

Thanks,
Marcelo Bittencourt, MD
Lab. TIM, ETS de Franche-Comt=E9
France