Dumb plant virus question

[muriel lederman]

>What is/are the mechanism(s) by which endogenous expression of plant
>virus coat proteins in transgenic plants result in virus resistance?
>Hopefully, this will be a straightforward question to someone out
>there, or is it just another example of one of thoses aspects of
>virus biology we really should understand, but don't? TIA,

Here's some help from another animal virologist who's doing a graduate
virology seminar in collaboration with a plant virologist - these
papers are to be discussed next week - impeccable timing!


"Genetic Engineering of Potyvirus Resistance Using Constructs Derived
for the Zucchini Yellow Mosaic Birus Coat Protein Gene"  Molecular
Plant-Microbe Interactions, Vol.6 No.3 pp. 358-367

"Transgenic Plant Virus Resistance Mediated by Untranslatable sense
RNAs: Expression, Regulation, and Fate of Nenessential RNAs" The Plant
Cell, Vol 6 1441-1453, Oct 1994

"Genetic and Biochemical Dissection of Transgenbic RNA-Mediated Virus
Resistance" The Plant Cell, Vol 8, pp 95-105, Jan 1996

"Mechanisnms of Pathogen Derived Resistance to Viruses in Transgenic
Plants." The Plant Cell, Vol 8, 1833-1844, Oct 1996 (review)

Muriel Lederman           lederman at vt.edu     540.231.5702 (phone)
Department of Biology                         540.231.9307 (fax)
Interim Coordinator, Biological Sciences
   Initiative
Virginia Tech
Blacksburg VA 24061-0406