Mouse virus, NOT bone-marrow derived cells?

Peter Charles pcharles at aecom.yu.edu
Tue Nov 12 11:48:09 EST 1996


Ian,

The lab that I did my grad work in does a lot of
work with Sindbis virus.  If memory serves (and sometimes
it doesn't...), SB didn't replicate in lymphoid cells.  Replication
was pretty much confined to fibroblasts, skeletal muscle, and
neural/glial type cells.  SB is relatively safe, grows to phenomenal
titers in cell culture, and is easy to purify.  You might want
to do a lit search to see if there is anything recent out there 
that I have missed.  Names of authors to check would be:

Johnston, R; Griffin, D; or Rice, C

Regards,

Peter C. Charles, PhD
Department of Pathology (Neuropathology)
Albert Einstein College of Medicine





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