BSE versus Creutzveld-Jacobs-syndrome

Tim Fitzmaurice tjf11 at cus.cam.ac.uk
Mon Apr 1 02:16:47 EST 1996


On 29 Mar 1996 bhjelle at unm.edu wrote:
> co.uk/bse/tse.htm.#immunity). BSE can be transmitted into
> transgenic mice bearing human PrP and produces human PrPSc.

Excuse me could you cite this paper, the only work of this kind that I 
have seen had transgenic mice infected with BSE, but those with were 
positive solely for Human PrP did not develop, and those which where human 
+ve/mouse +ve only developed mouse PrPsc....indicating a cattle to human
species barrier in the experiment but no cattle to mouse barrier.

Tim



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