Non pathogenic viruses

Vasconcelos Costa 385 jcosta at pen.gulbenkian.pt
Thu Sep 28 02:54:02 EST 1995


> From: Martin Hewlett <marty_hewlett at TIKAL.BIOSCI.ARIZONA.EDU>
> To: "bionet.virology mail newsgroup" <bionet-news at dl.ac.uk>
> Subject: Re: Non pathogenic viruses
> 
> If you have access to computers and the Web (which I assume you do) why 
> not work with viral genomic sequences rather than with the viruses 
> themselves?  Lots of interesting possibilities might exist, such as 
> comparative analyses, examination of possible translation products from 
> genomes and so forth.  The sequence analysis programs should be 
> available to you.
> 
> Martin Hewlett
> Associate Professor
> Department of Molecular and Cellular Biology
> University of Arizona
> Tucson, Arizona
> 
 
Like probably many other fellows in my professional situation, supervision,
direction and administrative tasks do not let me so much time for bench work.
So, helpingmy young people with biocomputing (sequence search, analysis, etc)
is one way of direct participation in the research work.
In this sense, I don't think your suggestion is very new. Besides, the work
in mol. biol. of viruses is very often a three-step work: 1. getting or
validating a hypothesis by computer work (comparisons, looking for probes,
finding motifs, etc.); 2. experimental work; 3. go back to the computer for
final analysis.
Sorry for what may be some "professoral style" of this message. This may
be due to the use of a foreign language.

Joao V. Costa

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