Re infectivity of naked viral DNA

[DANDERSON at PRL.PULMONARY.UBC.CA]

On 17 May 1995, Ed Rybicki wrote:

> > Subject:       Re infectivity of naked viral DNA
> 
> But you CAN inoculate cDNA clones of plant viruses (and I am sure, of 
> picornaviruses) into susceptible hosts, and get production of native 
> virus - 

You are correct, this has been performed with cell lines and 
picornavirus cDNA and RNA (wild-type RNA and RNA from the cDNA 
clone)! 

Dan