(none)

[Ian A. York]

In article <Pine.3.88.9505161130.B12672-0100000 at labsun1.med.uottawa.ca> kwright at LABSUN1.MED.UOTTAWA.CA ("kathryn wright ", microbiology) writes:
>
>To Chuckles:
>	The reference cited by S. Godvin (Ullmer et al.) does not show 
>that DNA is infectious, but that copies of an influenza gene in a 
>bacterial plasmid can be expresssed in a mammalian host.  This is not 
>"infection".

I'm not sure if this has been answered already.  However, I have the 
paper right in front of me, so I'll point out that in 
The tempo and mode of SIV quasispecies development in vivo calls for 
massive viral replication and clearance.  
Pelletier et al
Virology 208:644-652 (1995)

naked SIV DNA was injected into monkeys intramuscularly and they did 
develop infection.  Whether this very artificial system represents a 
physiological situation or not is another question.  

Ian
-- 
Ian York   (york at mbcrr.harvard.edu)
Dana-Farber Cancer Institute, 44 Binney St., Boston MA 02115
Phone (617)-632-3921     Fax  (617)-632-2627