Ebola references (long post)

[Gary Ross]

A few recent messages asked about references to Ebola virus.

Hope this helps.

-- Gary

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References to search on *Ebola* virus (from Dialog)
02.18.95


09031110   94346110
  *Ebola* hemorrhagic fever
  Gemorragicheskaia likhoradka *Ebola*.
  Titenko AM
  Zh Mikrobiol Epidemiol Immunobiol (RUSSIA)   May-Jun 1993,   (3) p99-105,
ISSN 0372-9311   Journal Code: Y9O
  Languages: RUSSIAN
  Document type: JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
  JOURNAL ANNOUNCEMENT: 9411
  Subfile:   INDEX MEDICUS
  (91 Refs.)
  Tags: Animal; Human
  Descriptors:  *Ebola*  Virus;  *Hemorrhagic  Fevers, Viral--Etiology--ET;
*Ebola* Virus--Genetics--GE;  *Ebola* Virus--Pathogenicity--PY; Hemorrhagic
Fevers, Viral--Diagnosis--DI;  Hemorrhagic Fevers, Viral--Epidemiology--EP;
 Hemorrhagic  Fevers,  Viral--Microbiology--MI;   Hemorrhagic Fevers, Viral
--Prevention and Control--PC; Risk Factors


09023611   94338611
  The laboratory, epidemiology, nosocomial infection and HIV [editorial]
  Heymann DL; Piot P
  AIDS (UNITED STATES)   May 1994,  8 (5) p705-6,  ISSN 0269-9370
Journal Code: AID
  Languages: ENGLISH
  Document type: EDITORIAL
  JOURNAL ANNOUNCEMENT: 9411
  Subfile:   INDEX MEDICUS
  Tags: Human
  Descriptors:  *Cross  Infection--Transmission--TM; *Genetics, Biochemical
--Methods--MT;  *HIV  Infections--Transmission--TM;  *HIV-1 --Isolation and
Purification--IP; *Infection Control--Standards--ST; *Virology--Methods--MT
;   Child;   Cohort   Studies;  Cross  Infection--Epidemiology--EP;   Cross
Infection--Microbiology--MI;   Cross Infection--Prevention and Control--PC;
Diphtheria--Epidemiology--EP;      Diphtheria--Transmission--TM;    Disease
Outbreaks;  *Ebola*  Virus;  Equipment  Contamination;  Hemorrhagic Fevers,
Viral--Epidemiology--EP;   Hemorrhagic Fevers, Viral--Transmission--TM; HIV
Infections--Epidemiology--EP;    HIV   Infections--Microbiology--MI;    HIV
Infections--Prevention  and  Control--PC; HIV-1--Classification--CL;  HIV-1
--Genetics--GE; Iatrogenic Disease; Injections--Adverse Effects--AE; Needle
Sharing;    Romania--Epidemiology--EP;    Russia--Epidemiology--EP;   Zaire
--Epidemiology--EP


09022509   94337509
  Research with the Marburg, Lassa and *Ebola* viruses]
  Issledovaniia s virusami Marburg, Lassa i *Ebola*.
  Pshenichnov VA; Makhlai AA; Mikhailov VV
  Vopr Virusol (RUSSIA)   Mar-Apr 1993,  38 (2) p54-8,  ISSN 0507-4088
Journal Code: XL8
  Languages: RUSSIAN
  Document type: JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
  JOURNAL ANNOUNCEMENT: 9411
  Subfile:   INDEX MEDICUS
  (53 Refs.)
  Tags: Animal; Human
  Descriptors: *Ebola* Virus; *Lassa Virus; *Marburg Virus; Disease Models,
Animal; *Ebola* Virus--Drug Effects--DE;  *Ebola* Virus--Pathogenicity--PY;
Hemorrhagic  Fevers, Viral--Diagnosis--DI;  Hemorrhagic Fevers, Viral--Drug
Therapy--DT;   Hemorrhagic  Fevers,  Viral--Microbiology--MI;  Lassa  Fever
--Diagnosis--DI;  Lassa Fever--Drug Therapy--DT;  Lassa Fever--Microbiology
--MI;   Lassa  Virus--Drug  Effects--DE;   Lassa  Virus--Pathogenicity--PY;
Marburg Virus--Drug Effects--DE;  Marburg Virus--Pathogenicity--PY; Marburg
Virus  Disease--Diagnosis--DI;   Marburg  Virus  Disease--Drug Therapy--DT;
 Marburg Virus Disease--Microbiology--MI; Research


08972666   94287666
  The isolation of hyperimmune horse serum to the *Ebola* virus]
  Poluchenie giperimmunnoi loshadinoi syvorotki k virusu *Ebola*.
  Krasnianskii  VP;  Mikhailov  VV; Borisevich IV; Gradoboev VN; Evseev AA;
Pshenichnov VA
  Vopr Virusol (RUSSIA)   Mar-Apr 1994,  39 (2) p91-2,  ISSN 0507-4088
Journal Code: XL8
  Languages: RUSSIAN   Summary Languages: ENGLISH
  Document type: JOURNAL ARTICLE   English Abstract
  JOURNAL ANNOUNCEMENT: 9409
  Subfile:   INDEX MEDICUS
  Immunization  of  horses with *Ebola* virus resulted in the production of
specific  virus-neutralizing  antibody  with  maximum titres at 28-42 days.
Repeated cycles of immunization led to a rise in antibody titres to 1:4096.
  Tags: Animal
  Descriptors:  *Ebola*  Virus--Immunology--IM; *Immune Sera--Isolation and
Purification--IP;   Antibodies,   Viral--Blood--BL;   Horses;  Immunization
--Methods--MT; Immunization, Secondary; Neutralization Tests; Time Factors


08972663   94287663
  The  evaluation  in hamadryas baboons of the possibility for the specific
prevention of *Ebola* fever]
  Otsenka    na    pavianakh   gamadrilakh   vozmozhnosti   spetsificheskoi
profilaktiki likhoradki *Ebola*.
  Mikhailov  VV;  Borisevich IV; Chernikova NK; Potryvaeva NV; Krasnianskii
VP
  Vopr Virusol (RUSSIA)   Mar-Apr 1994,  39 (2) p82-4,  ISSN 0507-4088
Journal Code: XL8
  Languages: RUSSIAN   Summary Languages: ENGLISH
  Document type: JOURNAL ARTICLE   English Abstract
  JOURNAL ANNOUNCEMENT: 9409
  Subfile:   INDEX MEDICUS
  The  protective  role  of virus-neutralizing antibody was demonstrated in
*Ebola* virus-infected animals (Papio hamadryas) used in experiments on the
development  of  passive humoral immunity by using specific immunoglobulin.
Two  immunizations  of the monkeys with purified concentrated *Ebola* virus
antigen  with  complete  Freund  adjuvant  was  shown  to confirm intensive
immunity  to  subsequent challenge protecting 80% of the immunized animals.
It  is  concluded that effective preparations may be developed for specific
prophylaxis of *Ebola* fever.
  Tags: Animal; Comparative Study; Female; Male
  Descriptors:  *Ebola*  Virus;  *Hemorrhagic Fevers, Viral--Prevention and
Control--PC;  *Monkey  Diseases--Prevention  and  Control--PC;  Antibodies,
Viral--Blood--BL;  Antibody  Specificity;  Antigens, Viral--Immunology--IM;
 Antigens, Viral--Isolation and Purification--IP; *Ebola* Virus--Immunology
--IM; Hemorrhagic Fevers, Viral--Immunology--IM; Immunization--Methods--MT;
Immunoglobulins--Immunology--IM;      Immunoglobulins    --Isolation    and
Purification--IP; Monkey Diseases--Immunology--IM; Papio; Time Factors
  CAS  Registry  No.:  0    (Antibodies,  Viral);  0   (Antigens, Viral); 0
 (Immunoglobulins)


08852883   94167883
  Characterization  of  filoviruses  based  on differences in structure and
antigenicity of the virion glycoprotein.
  Feldmann H; Nichol ST; Klenk HD; Peters CJ; Sanchez A
  Special  Pathogens  Branch,  Centers  for Disease Control and Prevention,
Atlanta, Georgia 30333.
  Virology (UNITED STATES)   Mar 1994,  199 (2) p469-73,  ISSN 0042-6822
Journal Code: XEA
  Languages: ENGLISH
  Document type: JOURNAL ARTICLE
  JOURNAL ANNOUNCEMENT: 9406
  Subfile:   INDEX MEDICUS
  Eight  different  filovirus  isolates,  representing  major  episodes  of
filovirus   hemorrhagic   disease,   were  propagated  for  structural  and
antigenetic  analyses  of  their  glycoprotein  (GP). Carbohydrate analysis
revealed  that  N-  and  O-glycosylation  are  features  of  filovirus GPs.
Oligosaccharide  side  chains  differed  in  their  sialylation pattern and
seemed  to be cell line-dependent. Marburg virus (MBG) isolates are clearly
distinguished  from  *Ebola* (EBO) and Reston viruses by a lack of terminal
sialic acids when propagated in E6 and MA-104 cells. It was also determined
that  GP-specific  antisera failed to show any cross-reactivity between MBG
isolates  and  other filoviruses. These data, together with prior findings,
indicate  that  the genus Filovirus can be divided into a MBG group and EBO
group.
  Tags: Animal; Human; Support, Non-U.S. Gov't
  Descriptors:  *Antigens,  Viral--Analysis--AN; *Filovirus--Chemistry--CH;
*Glycoproteins--Chemistry--CH; *Virion--Chemistry--CH; Cell Line; Filovirus
--Immunology--IM;   Glycoproteins--Immunology--IM;   Vero   Cells;   Virion
--Immunology--IM
  CAS Registry No.: 0   (Antigens, Viral); 0   (Glycoproteins)


08775702   94090702
  Filovirus  activity  among selected ethnic groups inhabiting the tropical
forest of equatorial Africa.
  Johnson ED; Gonzalez JP; Georges A
  United  States  Army  Medical  Research Institute of Infectious Diseases,
Frederick, Maryland.
  Trans  R Soc Trop Med Hyg (ENGLAND)   Sep-Oct 1993,  87 (5) p536-8,  ISSN
0035-9203   Journal Code: WBU
  Languages: ENGLISH
  Document type: JOURNAL ARTICLE
  JOURNAL ANNOUNCEMENT: 9403
  Subfile:   INDEX MEDICUS
  Seroepidemiological surveys were conducted to determine the frequency and
distribution  of filovirus activity among selected ethnic groups inhabiting
the  tropical  forests of the Central African Republic. 427 serum specimens
were  collected  from  hunter-gatherers  and  subsistence farmers living in
forest  environs  in the Lobaye District south of the river Lobaye and west
of the river Oubangui. Striking serological evidence for filovirus activity
was  found in both populations. *Ebola* virus appears to be the most active
filovirus; 17.6% (75/427) of the Lobaye survey population were seropositive
for  *Ebola*  virus  reactive antibody while 1.2% (5/427) were seroreactive
with  Marburg viral antigens. Ethnic background appeared to be an important
risk  factor  influencing filovirus exposure in the forest communities. The
filovirus  antibody  prevalence  among  21-40  years  old  male  Aka  Pygmy
hunter-gatherers  was  significantly (P = 0.03) 3 times higher (37.5%) than
that in similarly aged male Monzombo and Mbati subsistence farmers (13.2%).
Continued    epidemiological    investigations   are   needed   to   define
ethnic-related  events  influencing  human  filovirus activity in the Congo
basin of equatorial Africa.
  Tags: Comparative Study; Female; Human; Male
  Descriptors: *Antibodies, Viral--Analysis--AN; *Filovirus--Immunology--IM
;   *Hemorrhagic  Fevers,  Viral--Ethnology--EH;  Adolescence;  Adult;  Age
Factors;   Central   African   Republic--Epidemiology--EP;   Child;  Child,
Preschool;   *Ebola*   Virus--Immunology--IM;  Ethnic  Groups;  Hemorrhagic
Fevers,   Viral--Immunology--IM;   Infant;  Marburg  Virus--Immunology--IM;
Prevalence; Risk Factors; Rural Population
  CAS Registry No.: 0   (Antibodies, Viral)


08775701   94090701
  Haemorrhagic  fever virus activity in equatorial Africa: distribution and
prevalence of filovirus reactive antibody in the Central African Republic.
  Johnson ED; Gonzalez JP; Georges A
  United  States  Army  Medical  Research Institute of Infectious Diseases,
Frederick, Maryland.
  Trans  R Soc Trop Med Hyg (ENGLAND)   Sep-Oct 1993,  87 (5) p530-5,  ISSN
0035-9203   Journal Code: WBU
  Languages: ENGLISH
  Document type: JOURNAL ARTICLE
  JOURNAL ANNOUNCEMENT: 9403
  Subfile:   INDEX MEDICUS
  Seroepidemiological surveys were conducted to determine the frequency and
distribution  of  haemorrhagic  fever  virus  (HFV) activity in the Central
African  Republic.  Human  serum  specimens  (4295)  were  collected from 5
ecologically distinct zones. Serological evidence of HFV activity was found
in  all the zones. The filovirus antibody prevalence (24.4%, 1051/4295) was
greater  than  the  combined  prevalence for Lassa virus, Rift Valley fever
virus and Crimean-Congo HFV antibody (1.1%, 45/4295; P < 0.01). Evidence of
filovirus  activity  was  found  in  all  zones:  21.3%  (914/4295)  of the
population  were  seropositive  for  *Ebola* virus antibody while only 3.2%
(137/4295)  were seroreactive with Marburg viral antigens. Age and sex were
important host-related factors influencing filovirus activity, particularly
in  dry  grassland  and  moist forest communities. These communities shared
many  factors,  but  differences, such as agricultural practices and ethnic
backgrounds,  may  also  affect the risk of infection. Filovirus infections
appear  to  occur  without  apparent  disease. Continued investigations are
needed  to  evaluate  the true pathogenicity of the African filoviruses and
the   likelihood   that   unidentified   serologically  cross-reacting  and
non-pathogenic  members  of  the  filovirus family are active in equatorial
Africa.
  Tags: Female; Human; Male
  Descriptors: *Antibodies, Viral--Analysis--AN; *Filovirus--Immunology--IM
;  *Hemorrhagic  Fevers,  Viral--Epidemiology--EP;  Adolescence; Adult; Age
Factors;   Central   African   Republic--Epidemiology--EP;   Child;  Child,
Preschool;   Fluorescent  Antibody  Technique;  Hemorrhagic  Fevers,  Viral
--Immunology--IM; Infant; Prevalence; Sex Factors
  CAS Registry No.: 0   (Antibodies, Viral)


08764542   94079542
  *Ebola* protein analyses for the determination of genetic organization.
  Elliott LH; Sanchez A; Holloway BP; Kiley MP; McCormick JB
  Division  of  Viral and Rickettsial Diseases, Centers for Disease Control
and Prevention, Atlanta, Georgia.
  Arch Virol (AUSTRIA)   1993,  133 (3-4) p423-36,  ISSN 0304-8608
Journal Code: 8L7
  Languages: ENGLISH
  Document type: JOURNAL ARTICLE
  JOURNAL ANNOUNCEMENT: 9403
  Subfile:   INDEX MEDICUS
  Amino-acid  sequencing of the purified major nucleoprotein (NP), VP35 and
VP40  from purified *Ebola* virus proved that they are the protein products
of  the  first three genes, and that the open reading frame (ORF) of the NP
begins  at nucleotide 470. Because of the many unusual features of the ORFs
of  *Ebola* virus, we thought that our conclusions should be substantiated.
Comparisons  of  in  vitro-translation  products to purified viral proteins
were  used  to demonstrate conclusively that the NP, VP35 and VP40 were the
protein  products of genes one, two, and three, respectively. Studies using
antibodies  to  synthetic  peptides  matching  the  N- and C-termini of the
deduced sequences from these genes confirmed these conclusions and that the
ORF  for the NP begins at nucleotide 470. Subsequent studies confirmed that
VP30 is encoded by the fifth gene.
  Tags: Animal
  Descriptors:  *Ebola* Virus--Genetics--GE; *Genes, Viral; *Viral Proteins
--Chemistry--CH;  Amino  Acid  Sequence;  Blotting,  Western; Cercopithecus
aethiops;  Chromatography, High Pressure Liquid; Clone Cells; *Ebola* Virus
--Chemistry--CH;   Electrophoresis,   Polyacrylamide   Gel;   Enzyme-Linked
Immunosorbent  Assay;  Guinea Pigs; Molecular Sequence Data; Nucleoproteins
--Chemistry--CH;   Nucleoproteins--Genetics--GE;  Nucleoproteins--Isolation
and      Purification--IP;      Open      Reading     Frames--Genetics--GE;
Radioimmunoprecipitation  Assay;  Translation,  Genetic;  Vero Cells; Viral
Core  Proteins--Chemistry--CH;   Viral  Core Proteins--Genetics--GE;  Viral
Core Proteins--Isolation and Purification--IP; Viral Proteins--Genetics--GE
;  Viral Proteins--Isolation and Purification--IP
  CAS   Registry   No.:   0     (nucleoprotein   VP35,   Ebola   virus);  0
 (nucleoprotein  VP40,  Ebola  virus); 0   (Nucleoproteins); 0  (Viral Core
Proteins); 0   (Viral Proteins); 0   (VP35 protein); 0   (VP40 protein)


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