Diploid Viruses?
Heather D. Mayor
hmayor at bcm.tmc.edu
Thu Oct 27 13:53:45 EST 1994
In article <38oj6c$es6 at hermod.uio.no>, ohungnes at bioslave.uio.no (Olav
Hungnes) wrote:
>" Furthermore, the retrovirus particles contain two copies of the genomic RNA. >They will be "homozygous" if originating from a cell with only one provirus, >and may be "heterozygous" when incorporating transcripts from two different >proviruses ( probably random) in a mixed infection setting. Recombination >between the two copies seems to happen frequently: "
> Rearrangements and homologous recombination in retroviruses is quite
> common. The frequency of recombination is so high that two sites 1 kb
> apart is reported to segregate independently.
>
> Olav
> --
> _______________________________________________________
> Olav Hungnes olav.hungnes at embnet.uio.no
> National Institute Phone (+47)22042200
> of Public Health FAX (+47)22353605
> Oslo, NORWAY
> _______________________________________________________
--
Where is the published information that recombination between the two
copies of the retrovirus RNA occurs frequently?
*--------------------------------------------------------------*
H* Heather D. Mayor *D* hmayor at mbcr.bcm.tmc.edu *M
H* Department of Microbiology *D* OR *M
H* Baylor College of Medicine *D* hmayor at bcm.tmc.edu *M
H* 1 Baylor Plaza *D* VOICE 713-798-4929 *M
H* Houston, TX 77030 U.S.A. *D* FAX 713-798-7375 *M
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