JC Virus and PMLeukoenkephalopathy

[n.panjwani at ic.ac.uk]

I have come across mention that JC Virus and BK Virus, (which cause PML and
Haemorrhagic Cystitis, respectively on reactivation/reinfection), are
reactivated by pregnancy. I have no idea how pregnancy can cause
immunosuppression, so perhaps the cause is hormonal. Can anyone shed light
on how pregnancy reactivates latent human polyomaviruses (JCV and BKV)

Cheers,

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       |						|
       |		Naveed Panjwani			|		
       | London School of Hygiene and Tropical Medicine |
       | 	    University of London, UK		|
       |________________________________________________|