Acyclovir sensitivity testing

[Jack M. Bernstein, M.D.]

In article <3079kf$2gc at search01.news.aol.com> jeffschuh at aol.com (Jeff Schuh) writes:
>From: jeffschuh at aol.com (Jeff Schuh)
>Subject: Acyclovir sensitivity testing
>Date: 15 Jul 1994 20:29:03 -0400

>Our lab (SoCal Kaiser Regional Virology) has recently decided to try to
>bring Acyclovir sensitivity testing in house.  We're not really sure how
>to perform the assay and were wondering if anyone else had any suggestions
>or methodologies or had read any journal articles.  I don't think anything
>was at ICAAC but maybe I missed something.  We're hoping to use a modified
>plaque reduction assay but in microtiter format.  Thanks in advance

Ella Swierkosz (sp?) at St. Louis University has published on this in J Clin 
Micro. Look back through that journal for a couple of years and you should see 
some easy methods. Essentially they are looking at decreasing ELISA signal 
with increasing effect.

Jack Bernstein, M.D.