# Immune system engineering

See [[cell therapy]] for more information about immune system engineering.


## CAR T cell therapy

[In vivo CAR T cell generation to treat cancer and autoimmune disease](https://www.science.org/doi/10.1126/science.ads8473) -- a gene-delivery system to generate CAR-T cells in vivo by dosing of a CD8-targeted lipid nanoparticle carrying anti-CD19 CAR mRNA.

## various autologous stem cell therapy methods

## other immune system stuff

## diabetes

See [[diabetes]].

[Survival of transplanted allogeneic beta cells with no immunosuppression](https://www.nejm.org/doi/10.1056/NEJMoa2503822)

<a href="https://www.cell.com/cell/fulltext/S0092-8674(24)01022-5)">Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient</a>